Corresponding Author: Gerald C. Hsu, eclaireMD Foundation, USA.
The author applied his knowledge from advanced mathematics, physics concepts, engineering modeling, and computer science tools to re-examine the relationship with food, exercise, and postprandial plasma glucose (PPG) for one particular type 2 diabetes (T2D) patient, himself.
The focus of this paper is to apply energy theory specifically from physics and engineering on medicine. He used both optical physics and signal wave processing to develop his PPG prediction model. He realized that weight is merely a physical representation of internal energy exchange in the human body. The energy infusion includes food and others, whereas energy diffusion comprises of exercise/activity and others. The major goal is to avoid having energy imbalance known as disequilibrium; otherwise, the excessive (left-over) energy will circulate within the blood glucose to damage one’s internal organs.
The food/meal database contains ~8 million, while the patient’s metabolism data is ~1.5 million.
The 4,354 food/meals (3,927 meals and 427 snacks) in the selected period of 1,309 days (6/1/2015 – 12/31/2018) indicate the average values for daily glucose as 118.4 mg/dL and daily carbs/sugar intake as 15 grams per meal. After consuming carbs/sugar in the range of 2 to 22 grams, he walked 2,600 to 6,600 steps after each meal. The results showed that 94% of his total 3,927 PPG values would be lower than 120 mg/dL (Figure 1).
Figure 1: PPG vs Carbs/Sugar intake (49% correlation); PPG vs post-meal walking (-82%); Spatial analysis
Furthermore, by applying energy theory, he found a “preliminary” glucose-energy perturbation range of -13% to +8% resulting from left-over energy (Figure 2). In order to further narrow down the variance, he identified a few practical methods to improve both food intake and exercise in order to “wear-off” the excessive left-over energy.
Figure 2: PPG vs Energy generated from daily glucose (finger-piercing)
The author did not discover any major new findings during this research process. However, he adjusted some practical methods regarding the control of energy infusion through food intake and energy consumption by post-meal walking. Therefore, this set of practical tips can guide T2D patients to further improve their PPG conditions.